I've suffered for over a year with arthritis that is so severe in my thumb that it easily dislocates. When this happens, the pain is excruciating. Very few natural and over-the-counter products help with the pain with the exception of a localized application of a 10% dilution of Devil's club in Jojoba oil (wax). Just a quarter size of the blend is all that is needed to quickly and significantly reduce my pain. And although I have a foot bath every day with warm water and sea salt, the addition of Devil's club hydrosol I find helps relax my body even more.