Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.


​Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category
Component
Body System
Type
Title
Inflammation,Antibacterial,Cancer
Spathulenol
Reproductive,All
In Vivo
Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol
Enzymes
Spathulenol
N/A
In Vitro
Bioactive constituents of Conyza albida
Cancer
Alpha-Pinene,Globulol,Viridiflorene,Spathulenol
N/A
In Vitro
Chemical composition and cytotoxicity of oils and eremophilanes derived from various parts of Eremophila mitchellii Benth. (Myoporaceae)
Antifungal,Disease
Spathulenol
All
In Vitro
Antifungal activity of extracts of some plants used in Brazilian traditional medicine against the pathogenic fungus Paracoccidioides brasiliensis
Antiparasitic
Spathulenol,β-caryophyllene
N/A
In Vitro
In vitro antiparasitic activity and chemical composition of the essential oil from Protium ovatum leaves (Burceraceae)
Protectant
Spathulenol
Gastric
In Vivo
Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean Lamiaceae Sphacele chamaedryoides (Balbis) Briq
Antibacterial
Spathulenol
N/A
In Vitro
Volatiles from Subtropical Convolvulaceae That Interfere with Bacterial Cell-to-Cell Communication as Potential Antipathogenic Drugs
Anti-oxidant,Antibacterial
Alpha-Pinene,Beta-Pinene,β-caryophyllene,Germacrene D,Bicyclogermacrene
N/A
In Vitro
Gas Chromatography-Mass Spectrometry (GC-MS) and evaluation of antioxidant and antimicrobial activities of essential oil of Campomanesia adamantium (Cambess.) O. Berg (Guavira)
Antibacterial
1,10-di-epi-Cubenol
N/A
In Vitro
Composition of Three Essential Oils, and their Mammalian Cell Toxicity and Antimycobacterial Activity against Drug Resistant-Tuberculosis and Nontuberculous Mycobacteria Strains
Anti-oxidant
Nerolidol
N/A
In Vivo
Antioxidant Effects of Nerolidol in Mice Hippocampus After Open Field Test
Antiparasitic
Spathulenol
N/A
In Vitro
Biological Activities of the Essential Oil from Erigeron floribundus
Cancer
Spathulenol
Lung,Skin
In Vivo
Antitumour Activity of the Microencapsulation of Annona vepretorum Essential Oil
Cancer
Bicyclogermacrene,Spathulenol
N/A
In Vitro
Chemical Profile and in vitro Biological Activities of Essential Oils of Nectandra puberula and N. cuspidata from the Amazon
Covid-19
Bicyclogermacrene,β-caryophyllene
Lung
In Silico
Recognition of Natural Products as Potential Inhibitors of COVID‑19 Main Protease (Mpro): In‑Silico Evidences
Antifungal
Bicyclogermacrene
N/A
In Vitro
Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)
Antiparasitic
Bicyclogermacrene
N/A
In Vitro
Chemical composition and in vitro cytotoxic and antileishmanial activities of extract and essential oil from leaves of Piper cernuum
Antiparasitic
Bicyclogermacrene
N/A
In Vitro
In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species
Antibacterial,Anti-oxidant
Bicyclogermacrene
N/A
In Vivo
Chemical Composition and Antioxidant, Antimicrobial, and Larvicidal Activities of the Essential Oils of Annona salzmannii and A. pickelii (Annonaceae)
Cancer
Bicyclogermacrene
Skin,Brain,Reproductive,Colon,Breast
In Vitro
Chemical composition and in vitro cytotoxic effects of the essential oil from Nectandra leucantha leaves
Antifungal
Bicyclogermacrene,Spathulenol
Skin,Mouth
In Vitro,In Vivo
Antifungal activity of essential oils of Croton species from the Brazilian Caatinga biome
Antibacterial
Alpha-Muurolol
N/A
In Vivo
Cytotoxic Effect and TLC Bioautography-Guided Approach to Detect Health Properties of Amazonian Hedyosmum sprucei Essential Oil
Antibacterial
Alpha-Muurolol
N/A
In Vitro
Chemical Composition, Antifungal and Antioxidant Activities of Hedyosmum brasiliense Mart. ex Miq. (Chloranthaceae) Essential Oils
Muscle Relaxant
T-Cadinol
All
In Vitro
T-cadinol: a pharmacologically active constituent of scented myrrh: introductory pharmacological characterization and high field 1H- and 13C-NMR data
Protectant,Inflammation
Nerolidol
Heart
In Vivo
Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting cardiac inflammation and remodelling associated TLR4/ NF-κB signalling cascade
Toxicity,Protectant,Anti-oxidant
Related pharmacology
Spleen
In Vivo
MiR-182–5p/TLR4/NF-κB axis contributes to the protective effect of caffeic acid phenethyl ester against cadmium-induced spleen toxicity and associated damage in mice
Disease
Related pharmacology
All
In Silico
Pharmacological modulation of redox signaling pathways in disease
Cancer
Related pharmacology
N/A
In Vitro
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Disease
Related pharmacology
Kidney
In Vivo
L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
Anti-oxidant,Disease
Related pharmacology
Thyroid
In Vivo
The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism
Protectant
Related pharmacology
Heart
In Vivo
Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
Aging
Related pharmacology
N/A
In Vivo
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
Anti-oxidant,Protectant
Related pharmacology
N/A
In Vitro
Glucose availability is a decisive factor for Nrf2-mediated gene expression
Cancer
Related pharmacology
N/A
In Vitro
The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer
Disease
Related pharmacology
Heart
In Vitro,In Vivo
Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies
Cancer
Nerolidol
Liver
In Vitro
Nerolidol effects on mitochondrial and cellular energetics
Pharmacology
Oplopanax Horridus
All
In Vivo
TRADITIONAL USE OF DEVIL'S-CLUB (OPLOPANAX HORRIDUS; ARALIACEAE) BY NATIVE PEOPLES IN WESTERN NORTH AMERICA
Pharmacology,Cancer
Oplopanax Horridus
N/A
In Vitro
Oplopanax horridus: Phytochemistry and Pharmacological Diversity and Structure-Activity Relationship on Anticancer Effects
Cancer
Oplopanax Horridus
Lung,Breast
In Vitro
Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components
Antiparasitic
Nerolidol
N/A
In Vitro
Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum
Antiparasitic
Nerolidol
N/A
In Vitro
Terpenes Arrest Parasite Development and Inhibit Biosynthesis of Isoprenoids in Plasmodium falciparum
Insecticide
Nerolidol
N/A
In Vivo
Mosquito Repellent Potential of Carpesium abrotanoides Essential Oil and Its Main Components Against a Dengue Vector
Anti-oxidant,Protectant
Nerolidol
Heart,Kidney
In Vivo
The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
Inflammation,Disease
Nerolidol
Liver
In Vivo
Nerolidol protects the liver against cyclophosphamide-induced hepatic inflammation, apoptosis, and fibrosis via modulation of Nrf2, NF-κB p65, and caspase-3 signaling molecules in Swiss albino mice
Skin Permeation
Nerolidol
Skin
In Vitro
The effect of terpene concentrations on the skin penetration of diclofenac sodium
Anti-oxidant,Disease
Nerolidol
Heart
In Vivo
Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats
Anti-oxidant,Cancer
Nerolidol
N/A
In Vivo
Anticancer and antioxidant profiling effects of Nerolidol against DMBA induced oral experimental carcinogenesis
Cancer
Nerolidol
Bone
In Vitro
Nerolidol induced apoptosis via PI3K/JNK regulation through cell cycle arrest in MG-63 osteosarcoma cells
Anti-oxidant,Arthritis,Inflammation
Nerolidol
Skeletal
In Vivo
Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model
Antibacterial
Nerolidol
N/A
In Vitro
Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol
Antibacterial
Nerolidol
N/A
In Vitro
Effect of the essential oils from Piper sp. and blue led lights in the enhancement of the antibiotic activity of drugs against mdr bacterial strains
Antibacterial
Nerolidol
N/A
In Vitro
Evaluation of the antioxidant, antibacterial, and antibiofilm activity of the sesquiterpene nerolidol
Anti-oxidant,Protectant
Nerolidol
N/A
In Vivo
Dietary supplementation with nerolidol improves the antioxidant capacity and muscle fatty acid profile of Brycon amazonicus exposed to acute heat stress
Inflammation,Anti-oxidant
Nerolidol
Colon
In Vivo
Nerolidol, a sesquiterpene, attenuates oxidative stress and inflammation in acetic acid-induced colitis in rats
Protectant,Anxiolytic
Nerolidol
Nervous System
In Vivo
Assessment of anxiolytic effect of nerolidol in mice
Protectant
Alpha-Pinene
Nervous System
In Vivo
Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
Protectant,Anti-oxidant,Disease
Related pharmacology
Nervous System
In Vivo
Transcriptional Regulation by Nrf2
Pharmacology
Related pharmacology
Nervous System
In Vitro
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
Anti-oxidant,Protectant
Related pharmacology
Brain
In Vitro
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
Degenerative,Protectant,Disease
Related pharmacology
Nervous System
In Vitro,In Vivo
Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Anti-oxidant,Protectant,Disease
Related pharmacology
Kidney
In Vitro
Keap1/Nrf2/ARE signaling unfolds therapeutic targets for redox imbalanced-mediated diseases and diabetic nephropathy
Anti-oxidant,Disease
Related pharmacology
Immune System
In Vitro
How the redox state regulates immunity
Anti-oxidant
Related pharmacology
Nervous System
In Vitro,In Vivo
Nrf2-Keap1 signaling in oxidative and reductive stress
Inflammation
Related pharmacology
Nervous System
In Vitro,In Vivo
Nrf2 signaling pathway: Pivotal roles in inflammation
Protectant
Related pharmacology
Nervous System
In Vitro
The emerging role of Nrf2 in mitochondrial function
Protectant,Degenerative
Related pharmacology
Nervous System
In Silico,In Vitro
Structural basis of Keap1 interactions with Nrf2
Inflammation,Toxicity
Nerolidol
Nervous System
In Vivo
Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1
Aging,Degenerative
Related pharmacology
Brain
In Vivo
Selective noradrenaline depletion impairs working memory and hippocampal neurogenesis
Antibacterial
Torreyol
N/A
In Vitro
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN
Inflammation,Anti-oxidant
Related pharmacology
Nervous System
In Silico,In Vitro
Neurobiological Basis of Increased Risk for Suicidal Behaviour
Covid-19,Metabolism
Related pharmacology
All
In Vivo
Metabolic rewiring and serotonin depletion in patients with postacute sequelae of COVID-19
Disease,Aging,Anti-oxidant,Protectant,Degenerative
Related pharmacology
Nervous System,Cellular
In Silico
Redox regulation by NRF2 in aging and disease
Anti-oxidant
Related pharmacology
Kidney
In Vivo
L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
Protectant
Related pharmacology
Cellular
In Silico,In Vitro
Beyond repression of Nrf2: An update on Keap1
Pharmacology
Related pharmacology
Immune System
In Vitro
ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen
Cancer
Oplopanax Horridus
Colon,Breast
In Vitro
Hydrophobic constituents and their potential anticancer activities from Devil’s Club Oplopanax horridus
Protectant
Nerolidol
Heart
In Vivo
Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling
Protectant
Nerolidol
Lung
In Vivo
Protective effect of nerolidol on lipopolysaccharide-induced acute lung injury through the inhibition of NF-κB activation by the reduction of p38 MAPK and JNK phosphorylation
Protectant
Nerolidol
Liver,Bone
In Vivo
Effect of nerolidol on cyclophosphamide-induced bone marrow and hematologic toxicity in Swiss albino mice
Anti-oxidant,Antibacterial
Nerolidol
Brain
In Vivo
Benefits of nanotechnology: Dietary supplementation with nerolidol-loaded nanospheres increases survival rates, reduces bacterial loads and prevents oxidative damage in brains of Nile tilapia experimentally infected by Streptococcus agalactiae
Antiparasitic
Nerolidol
N/A
In Vitro
In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway
Women's Health
Nerolidol
Reproductive
In Silico
An Assay on the Possible Effect of Essential Oil Constituents on Receptors Involved in Women’s Hormonal Health and Reproductive System Diseases
Skin Permeation
Nerolidol
Skin
In Vitro
Toxicity of terpenes on fibroblast cells compared to their hemolytic potential and increase in erythrocyte membrane fluidity
Insecticide
Nerolidol
N/A
In Vivo
Toxicity of Juniperus oxycedrus oil constituents and related compounds and the efficacy of oil spray formulations to Dermatophagoides farinae (Acari: Pyroglyphidae)
Antifungal
Nerolidol
N/A
In Vitro
The Sensitivity Modifying Activity of Nerolidol and α-Bisabolol Against Trichophyton spp
Protectant,Anti-oxidant
Nerolidol
All
In Vitro,In Vivo
Terpenoids as Potential Geroprotectors
Covid-19
Related pharmacology
Lung
In Vitro
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Covid-19
Nerolidol
Lung
In Silico,In Vitro
Role of botanical essential oils as a therapy for controlling coronavirus (SARS-CoV-2) disease (Covid-19)
Protectant,Anti-oxidant
Nerolidol
Nervous System,Brain
In Vivo
Protective Effect of Nerolidol Against Pentylenetetrazol-Induced Kindling, Oxidative Stress and Associated Behavioral Comorbidities in Mice
Inflammation
Nerolidol
All
In Vivo,In Vitro
A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
Pharmacology
β-caryophyllene,Nerolidol
Liver
In Vitro,In Silico
B-caryophyllene Oxide and Trans-nerolidol Affect Enzyme Activity of CYP3A4 - In Vitro and In Silico Studies
Cancer,Anti-emitic
Nerolidol
All
In Vivo
Parapheromones Suppress Chemotherapy Side Effects
Inflammation
Nerolidol
Colon
In Vitro,In Vivo
Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models
Covid-19
Nerolidol
Lung
In Vitro,In Vivo
Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19
Arthritis,Inflammation
Related pharmacology
Skeletal
In Vivo,In Vitro
Neutrophil function in inflammation and inflammatory diseases
Protectant
Nerolidol
Head,Nervous System
In Vivo
Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats
Anti-oxidant,Inflammation
Nerolidol
Nervous System
In Vivo
Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone
Cancer
Nerolidol
Lung,Breast,Skin,Colon,Pancreas,Reproductive
In Vitro
Phytochemical investigations and antiproliferative secondary metabolites from Thymus alternans growing in Slovakia
Anti-oxidant,Inflammation
Nerolidol
Heart
In Vivo
Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats
Skin Permeation
Nerolidol
Skin
In Vitro
Effects of terpenes on fluidity and lipid extraction in phospholipid membranes
Protectant
Nerolidol
Kidney
In Vivo
Nerolidol Protects Against LPS-induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Signaling
Antifungal
Nerolidol
Eye
In Vitro
Nerolidol inhibits the LOX-1 / IL-1β signaling to protect against the Aspergillus fumigatus keratitis inflammation damage to the cornea
Inflammation
Nerolidol
Lung
In Vivo
Nerolidol Suppresses the Inflammatory Response during Lipopolysaccharide-Induced Acute Lung Injury via the Modulation of Antioxidant Enzymes and the AMPK/Nrf-2/HO-1 Pathway
Anti-nociceptive,Pain Management,Inflammation
Nerolidol
All
In Vivo
Nerolidol exhibits antinociceptive and anti‐inflammatory activity: involvement of the GABAergic system and proinflammatory cytokines
Pharmacology
Nerolidol
Liver
In Vivo
Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
Anti-oxidant,Inflammation
Nerolidol
Nervous System
In Vivo
Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB
Toxicity
Nerolidol
N/A
N/A
Addendum to Fragrance material review on Nerolidol (isomer unspecified)
Anti-diabetic
Nerolidol
Liver
In Vitro
Invitroantidiabetic Activity of Nerolidol: An Active Compound Isolated From Alpinia Calcarata
Antiparasitic
Nerolidol
N/A
In Vivo
Inhibitory effect of terpene nerolidol on the growth of Babesia parasites
Toxicity
Nerolidol
All
In Vivo
In vivo genotoxicity assessment of nerolidol
Antiviral,Covid-19
Nerolidol
Lung
In Silico
Essential Oils as Antiviral Agents, Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation
Antiparasitic,Disease,Antibacterial,Cancer,Wound Healing,Anti-oxidant,Protectant,Skin Permeation
Nerolidol
All
In Vitro,In Vivo
Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities
Protectant
Nerolidol
Liver
In Vitro
Hepatoprotection of sesquiterpenoids: A quantitative structure–activity relationship (QSAR) approach
Anti-oxidant,Cancer
Related pharmacology
Liver
In Vitro
THE POWER OF THE NRF2 PATHWAY
Safety
Nerolidol
N/A
N/A
BIOPESTICIDES REGISTRATION ACTION DOCUMENT: FARNESOL AND NEROLIDOL
Safety,Drug Interactions
Nerolidol
Liver
N/A
https://www.pharmacytimes.com/view/2007-11-8279
Insecticide
Nerolidol
Skin
In Silico
Design of a Repellent Against Aedes aegypti (Diptera: Culicidae) Using in silico Simulations With AaegOBP1 Protein
Cancer
Nerolidol
Lung
In Vitro
Cytotoxic mechanism of Piper gaudichaudianum Kunth essential oil and its major compound nerolidol
Pharmacology,Disease,Degenerative
Related pharmacology
N/A
In Vivo,In Vitro
The clinical potential of influencing Nrf2 signaling in degenerative and immunological disorders
Covid-19
Nerolidol
Lung
In Vivo,In Silico,In Vitro
Can Costus afer be used for co-treatment of COVID-19, its symptoms and comorbidities? A novel approach for combating the pandemic and implications for sub-Saharan Africa
Wound Healing
Nerolidol
Skin
In Vivo
Chitosan Hydrogel in combination with Nerolidol for healing wounds
Antibacterial
Nerolidol
N/A
In Vitro
Sensitization of Staphylococcus aureus and Escherichia coli to Antibiotics by the Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, and Apritone
Toxicity,Sensitivity
Nerolidol
N/A
In Vitro
A safety assessment of non-cyclic alcohols with unsaturated branched chain when used as fragrance ingredients: The RIFM expert panel
Disease,Covid-19,Antiviral,Inflammation
Nerolidol
Lung
In Vivo
COVID‑19 and therapy with essential oils having antiviral, anti‑inflammatory, and immunomodulatory properties
Antiparasitic
Nerolidol
N/A
In Vivo
Antiparasitic activity of nerolidol in a mouse model of schistosomiasis
Antibacterial
Nerolidol
Mouth
In Vitro
Antimicrobial potential of toothpaste formulated from extracts of Syzygium aromaticum, Dennettia tripetala and Jatropha curcas latex against some oral pathogenic microorganisms
Arthritis,Inflammation
Nerolidol
Joints
In Vivo
Anti-inflammatory effect of nano-encapsulated nerolidol on zymosan-induced arthritis in mice
Antifungal
Nerolidol
Skin
In Vitro
Antifungal Properties of Nerolidol-Containing Liposomes in Association with Fluconazole
Anti-oxidant
Nerolidol
Nervous System
In Silico
Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy
Men's Health
Nerolidol
Reproductive
In Vivo
Ameliorative effect of nerolidol on cyclophosphamide-induced gonadal toxicity in Swiss Albino mice: Biochemical-, histological- and immunohistochemical-based evidences
Anti-oxidant
Nerolidol
Heart,Kidney
In Vivo
The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
Antiparasitic
Nerolidol
Head
In Vivo
Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs
Inflammation
Nerolidol
N/A
In Vivo
A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
Disease
Nerolidol
Nervous System
In Silico
Nerolidol and its Pharmacological Application in Treating Neurodegenerative Diseases: A Review
Inflammation
Nerolidol
Liver
In Vivo
Downregulation of hepatic fat accumulation, inflammation and fibrosis by nerolidol in purpose built western-diet-induced multiple-hit pathogenesis of NASH animal model
Cancer
Nerolidol
Colon
In Vivo
Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-l,6,10-dodecatriene (nerolidol)
Men's Health
Nerolidol
Reproductive
In Vitro,In Vivo
Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants
Antibacterial,Skin Permeation
Nerolidol
N/A
In Vitro
Effects of nerolidol and limonene on stratum corneum membranes: A probe EPR and fluorescence spectroscopy study
Antibacterial
Nerolidol
N/A
In Vitro
Selection of nerolidol among a series of terpenic and phenolic compounds for its potent activity against Lactobacillus fermentum ATCC 9338
Antibacterial
Nerolidol
Colon
In Vitro
Sensitivity of pathogenic and commensal bacteria from the human colon to essential oils
Enzymes
Nerolidol
Liver
In Vitro
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
Women's Health
Nerolidol
N/A
In Vivo
Subfertile Female Androgen Receptor Knockout Mice Exhibit Defects in Neuroendocrine Signaling, Intraovarian Function, and Uterine Development But Not Uterine Function
Synergy,Metabolism
Nerolidol,β-caryophyllene
N/A
In Vivo
The impact of sesquiterpenes β-caryophyllene oxide and trans-nerolidol on xenobiotic-metabolizing enzymes in mice in vivo
Women's Health
Nerolidol
N/A
In Vivo
The beneficial effects of nerolidol and hesperidin on surgically induced endometriosis in a rat model