Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.

Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category	Component	Body System	Type	Title
Inflammation,Antibacterial,Cancer	Spathulenol	Reproductive,All	In Vivo	Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol
Enzymes	Spathulenol	N/A	In Vitro	Bioactive constituents of Conyza albida
Cancer	Alpha-Pinene,Globulol,Viridiflorene,Spathulenol	N/A	In Vitro	Chemical composition and cytotoxicity of oils and eremophilanes derived from various parts of Eremophila mitchellii Benth. (Myoporaceae)
Antifungal,Disease	Spathulenol	All	In Vitro	Antifungal activity of extracts of some plants used in Brazilian traditional medicine against the pathogenic fungus Paracoccidioides brasiliensis
Antiparasitic	Spathulenol,β-caryophyllene	N/A	In Vitro	In vitro antiparasitic activity and chemical composition of the essential oil from Protium ovatum leaves (Burceraceae)
Protectant	Spathulenol	Gastric	In Vivo	Gastroprotective effect and cytotoxicity of abietane diterpenes from the Chilean Lamiaceae Sphacele chamaedryoides (Balbis) Briq
Antibacterial	Spathulenol	N/A	In Vitro	Volatiles from Subtropical Convolvulaceae That Interfere with Bacterial Cell-to-Cell Communication as Potential Antipathogenic Drugs
Anti-oxidant,Antibacterial	Alpha-Pinene,Beta-Pinene,β-caryophyllene,Germacrene D,Bicyclogermacrene	N/A	In Vitro	Gas Chromatography-Mass Spectrometry (GC-MS) and evaluation of antioxidant and antimicrobial activities of essential oil of Campomanesia adamantium (Cambess.) O. Berg (Guavira)
Antibacterial	1,10-di-epi-Cubenol	N/A	In Vitro	Composition of Three Essential Oils, and their Mammalian Cell Toxicity and Antimycobacterial Activity against Drug Resistant-Tuberculosis and Nontuberculous Mycobacteria Strains
Anti-oxidant	Nerolidol	N/A	In Vivo	Antioxidant Effects of Nerolidol in Mice Hippocampus After Open Field Test
Antiparasitic	Spathulenol	N/A	In Vitro	Biological Activities of the Essential Oil from Erigeron floribundus
Cancer	Spathulenol	Lung,Skin	In Vivo	Antitumour Activity of the Microencapsulation of Annona vepretorum Essential Oil
Cancer	Bicyclogermacrene,Spathulenol	N/A	In Vitro	Chemical Profile and in vitro Biological Activities of Essential Oils of Nectandra puberula and N. cuspidata from the Amazon
Covid-19	Bicyclogermacrene,β-caryophyllene	Lung	In Silico	Recognition of Natural Products as Potential Inhibitors of COVID‑19 Main Protease (Mpro): In‑Silico Evidences
Antifungal	Bicyclogermacrene	N/A	In Vitro	Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)
Antiparasitic	Bicyclogermacrene	N/A	In Vitro	Chemical composition and in vitro cytotoxic and antileishmanial activities of extract and essential oil from leaves of Piper cernuum
Antiparasitic	Bicyclogermacrene	N/A	In Vitro	In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species
Antibacterial,Anti-oxidant	Bicyclogermacrene	N/A	In Vivo	Chemical Composition and Antioxidant, Antimicrobial, and Larvicidal Activities of the Essential Oils of Annona salzmannii and A. pickelii (Annonaceae)
Cancer	Bicyclogermacrene	Skin,Brain,Reproductive,Colon,Breast	In Vitro	Chemical composition and in vitro cytotoxic effects of the essential oil from Nectandra leucantha leaves
Antifungal	Bicyclogermacrene,Spathulenol	Skin,Mouth	In Vitro,In Vivo	Antifungal activity of essential oils of Croton species from the Brazilian Caatinga biome
Antibacterial	Alpha-Muurolol	N/A	In Vivo	Cytotoxic Effect and TLC Bioautography-Guided Approach to Detect Health Properties of Amazonian Hedyosmum sprucei Essential Oil
Antibacterial	Alpha-Muurolol	N/A	In Vitro	Chemical Composition, Antifungal and Antioxidant Activities of Hedyosmum brasiliense Mart. ex Miq. (Chloranthaceae) Essential Oils
Muscle Relaxant	T-Cadinol	All	In Vitro	T-cadinol: a pharmacologically active constituent of scented myrrh: introductory pharmacological characterization and high field 1H- and 13C-NMR data
Protectant,Inflammation	Nerolidol	Heart	In Vivo	Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting cardiac inflammation and remodelling associated TLR4/ NF-κB signalling cascade
Toxicity,Protectant,Anti-oxidant	Related pharmacology	Spleen	In Vivo	MiR-182–5p/TLR4/NF-κB axis contributes to the protective effect of caffeic acid phenethyl ester against cadmium-induced spleen toxicity and associated damage in mice
Disease	Related pharmacology	All	In Silico	Pharmacological modulation of redox signaling pathways in disease
Cancer	Related pharmacology	N/A	In Vitro	Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Disease	Related pharmacology	Kidney	In Vivo	L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
Anti-oxidant,Disease	Related pharmacology	Thyroid	In Vivo	The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism
Protectant	Related pharmacology	Heart	In Vivo	Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
Aging	Related pharmacology	N/A	In Vivo	Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
Anti-oxidant,Protectant	Related pharmacology	N/A	In Vitro	Glucose availability is a decisive factor for Nrf2-mediated gene expression
Cancer	Related pharmacology	N/A	In Vitro	The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer
Disease	Related pharmacology	Heart	In Vitro,In Vivo	Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies
Cancer	Nerolidol	Liver	In Vitro	Nerolidol effects on mitochondrial and cellular energetics
Pharmacology	Oplopanax Horridus	All	In Vivo	TRADITIONAL USE OF DEVIL'S-CLUB (OPLOPANAX HORRIDUS; ARALIACEAE) BY NATIVE PEOPLES IN WESTERN NORTH AMERICA
Pharmacology,Cancer	Oplopanax Horridus	N/A	In Vitro	Oplopanax horridus: Phytochemistry and Pharmacological Diversity and Structure-Activity Relationship on Anticancer Effects
Cancer	Oplopanax Horridus	Lung,Breast	In Vitro	Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components
Antiparasitic	Nerolidol	N/A	In Vitro	Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum
Antiparasitic	Nerolidol	N/A	In Vitro	Terpenes Arrest Parasite Development and Inhibit Biosynthesis of Isoprenoids in Plasmodium falciparum
Insecticide	Nerolidol	N/A	In Vivo	Mosquito Repellent Potential of Carpesium abrotanoides Essential Oil and Its Main Components Against a Dengue Vector
Anti-oxidant,Protectant	Nerolidol	Heart,Kidney	In Vivo	The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
Inflammation,Disease	Nerolidol	Liver	In Vivo	Nerolidol protects the liver against cyclophosphamide-induced hepatic inflammation, apoptosis, and fibrosis via modulation of Nrf2, NF-κB p65, and caspase-3 signaling molecules in Swiss albino mice
Skin Permeation	Nerolidol	Skin	In Vitro	The effect of terpene concentrations on the skin penetration of diclofenac sodium
Anti-oxidant,Disease	Nerolidol	Heart	In Vivo	Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats
Anti-oxidant,Cancer	Nerolidol	N/A	In Vivo	Anticancer and antioxidant profiling effects of Nerolidol against DMBA induced oral experimental carcinogenesis
Cancer	Nerolidol	Bone	In Vitro	Nerolidol induced apoptosis via PI3K/JNK regulation through cell cycle arrest in MG-63 osteosarcoma cells
Anti-oxidant,Arthritis,Inflammation	Nerolidol	Skeletal	In Vivo	Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model
Antibacterial	Nerolidol	N/A	In Vitro	Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol
Antibacterial	Nerolidol	N/A	In Vitro	Effect of the essential oils from Piper sp. and blue led lights in the enhancement of the antibiotic activity of drugs against mdr bacterial strains
Antibacterial	Nerolidol	N/A	In Vitro	Evaluation of the antioxidant, antibacterial, and antibiofilm activity of the sesquiterpene nerolidol
Anti-oxidant,Protectant	Nerolidol	N/A	In Vivo	Dietary supplementation with nerolidol improves the antioxidant capacity and muscle fatty acid profile of Brycon amazonicus exposed to acute heat stress
Inflammation,Anti-oxidant	Nerolidol	Colon	In Vivo	Nerolidol, a sesquiterpene, attenuates oxidative stress and inflammation in acetic acid-induced colitis in rats
Protectant,Anxiolytic	Nerolidol	Nervous System	In Vivo	Assessment of anxiolytic effect of nerolidol in mice
Protectant	Alpha-Pinene	Nervous System	In Vivo	Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
Protectant,Anti-oxidant,Disease	Related pharmacology	Nervous System	In Vivo	Transcriptional Regulation by Nrf2
Pharmacology	Related pharmacology	Nervous System	In Vitro	Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
Anti-oxidant,Protectant	Related pharmacology	Brain	In Vitro	Nrf2 regulates ROS production by mitochondria and NADPH oxidase
Degenerative,Protectant,Disease	Related pharmacology	Nervous System	In Vitro,In Vivo	Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Anti-oxidant,Protectant,Disease	Related pharmacology	Kidney	In Vitro	Keap1/Nrf2/ARE signaling unfolds therapeutic targets for redox imbalanced-mediated diseases and diabetic nephropathy
Anti-oxidant,Disease	Related pharmacology	Immune System	In Vitro	How the redox state regulates immunity
Anti-oxidant	Related pharmacology	Nervous System	In Vitro,In Vivo	Nrf2-Keap1 signaling in oxidative and reductive stress
Inflammation	Related pharmacology	Nervous System	In Vitro,In Vivo	Nrf2 signaling pathway: Pivotal roles in inflammation
Protectant	Related pharmacology	Nervous System	In Vitro	The emerging role of Nrf2 in mitochondrial function
Protectant,Degenerative	Related pharmacology	Nervous System	In Silico,In Vitro	Structural basis of Keap1 interactions with Nrf2
Inflammation,Toxicity	Nerolidol	Nervous System	In Vivo	Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1
Aging,Degenerative	Related pharmacology	Brain	In Vivo	Selective noradrenaline depletion impairs working memory and hippocampal neurogenesis
Antibacterial	Torreyol	N/A	In Vitro	ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN
Inflammation,Anti-oxidant	Related pharmacology	Nervous System	In Silico,In Vitro	Neurobiological Basis of Increased Risk for Suicidal Behaviour
Covid-19,Metabolism	Related pharmacology	All	In Vivo	Metabolic rewiring and serotonin depletion in patients with postacute sequelae of COVID-19
Disease,Aging,Anti-oxidant,Protectant,Degenerative	Related pharmacology	Nervous System,Cellular	In Silico	Redox regulation by NRF2 in aging and disease
Anti-oxidant	Related pharmacology	Kidney	In Vivo	L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
Protectant	Related pharmacology	Cellular	In Silico,In Vitro	Beyond repression of Nrf2: An update on Keap1
Pharmacology	Related pharmacology	Immune System	In Vitro	ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen
Cancer	Oplopanax Horridus	Colon,Breast	In Vitro	Hydrophobic constituents and their potential anticancer activities from Devil’s Club Oplopanax horridus
Protectant	Nerolidol	Heart	In Vivo	Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling
Protectant	Nerolidol	Lung	In Vivo	Protective effect of nerolidol on lipopolysaccharide-induced acute lung injury through the inhibition of NF-κB activation by the reduction of p38 MAPK and JNK phosphorylation
Protectant	Nerolidol	Liver,Bone	In Vivo	Effect of nerolidol on cyclophosphamide-induced bone marrow and hematologic toxicity in Swiss albino mice
Anti-oxidant,Antibacterial	Nerolidol	Brain	In Vivo	Benefits of nanotechnology: Dietary supplementation with nerolidol-loaded nanospheres increases survival rates, reduces bacterial loads and prevents oxidative damage in brains of Nile tilapia experimentally infected by Streptococcus agalactiae
Antiparasitic	Nerolidol	N/A	In Vitro	In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway
Women's Health	Nerolidol	Reproductive	In Silico	An Assay on the Possible Effect of Essential Oil Constituents on Receptors Involved in Women’s Hormonal Health and Reproductive System Diseases
Skin Permeation	Nerolidol	Skin	In Vitro	Toxicity of terpenes on fibroblast cells compared to their hemolytic potential and increase in erythrocyte membrane fluidity
Insecticide	Nerolidol	N/A	In Vivo	Toxicity of Juniperus oxycedrus oil constituents and related compounds and the efficacy of oil spray formulations to Dermatophagoides farinae (Acari: Pyroglyphidae)
Antifungal	Nerolidol	N/A	In Vitro	The Sensitivity Modifying Activity of Nerolidol and α-Bisabolol Against Trichophyton spp
Protectant,Anti-oxidant	Nerolidol	All	In Vitro,In Vivo	Terpenoids as Potential Geroprotectors
Covid-19	Related pharmacology	Lung	In Vitro	SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Covid-19	Nerolidol	Lung	In Silico,In Vitro	Role of botanical essential oils as a therapy for controlling coronavirus (SARS-CoV-2) disease (Covid-19)
Protectant,Anti-oxidant	Nerolidol	Nervous System,Brain	In Vivo	Protective Effect of Nerolidol Against Pentylenetetrazol-Induced Kindling, Oxidative Stress and Associated Behavioral Comorbidities in Mice
Inflammation	Nerolidol	All	In Vivo,In Vitro	A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
Pharmacology	β-caryophyllene,Nerolidol	Liver	In Vitro,In Silico	B-caryophyllene Oxide and Trans-nerolidol Affect Enzyme Activity of CYP3A4 - In Vitro and In Silico Studies
Cancer,Anti-emitic	Nerolidol	All	In Vivo	Parapheromones Suppress Chemotherapy Side Effects
Inflammation	Nerolidol	Colon	In Vitro,In Vivo	Nerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models
Covid-19	Nerolidol	Lung	In Vitro,In Vivo	Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19
Arthritis,Inflammation	Related pharmacology	Skeletal	In Vivo,In Vitro	Neutrophil function in inflammation and inflammatory diseases
Protectant	Nerolidol	Head,Nervous System	In Vivo	Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats
Anti-oxidant,Inflammation	Nerolidol	Nervous System	In Vivo	Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone
Cancer	Nerolidol	Lung,Breast,Skin,Colon,Pancreas,Reproductive	In Vitro	Phytochemical investigations and antiproliferative secondary metabolites from Thymus alternans growing in Slovakia
Anti-oxidant,Inflammation	Nerolidol	Heart	In Vivo	Nerolidol Attenuates Oxidative Stress, Inflammation, and Apoptosis by Modulating Nrf2/MAPK Signaling Pathways in Doxorubicin-Induced Acute Cardiotoxicity in Rats
Skin Permeation	Nerolidol	Skin	In Vitro	Effects of terpenes on fluidity and lipid extraction in phospholipid membranes
Protectant	Nerolidol	Kidney	In Vivo	Nerolidol Protects Against LPS-induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Signaling
Antifungal	Nerolidol	Eye	In Vitro	Nerolidol inhibits the LOX-1 / IL-1β signaling to protect against the Aspergillus fumigatus keratitis inflammation damage to the cornea
Inflammation	Nerolidol	Lung	In Vivo	Nerolidol Suppresses the Inflammatory Response during Lipopolysaccharide-Induced Acute Lung Injury via the Modulation of Antioxidant Enzymes and the AMPK/Nrf-2/HO-1 Pathway
Anti-nociceptive,Pain Management,Inflammation	Nerolidol	All	In Vivo	Nerolidol exhibits antinociceptive and anti‐inflammatory activity: involvement of the GABAergic system and proinflammatory cytokines
Pharmacology	Nerolidol	Liver	In Vivo	Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
Anti-oxidant,Inflammation	Nerolidol	Nervous System	In Vivo	Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB
Toxicity	Nerolidol	N/A	N/A	Addendum to Fragrance material review on Nerolidol (isomer unspecified)
Anti-diabetic	Nerolidol	Liver	In Vitro	Invitroantidiabetic Activity of Nerolidol: An Active Compound Isolated From Alpinia Calcarata
Antiparasitic	Nerolidol	N/A	In Vivo	Inhibitory effect of terpene nerolidol on the growth of Babesia parasites
Toxicity	Nerolidol	All	In Vivo	In vivo genotoxicity assessment of nerolidol
Antiviral,Covid-19	Nerolidol	Lung	In Silico	Essential Oils as Antiviral Agents, Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation
Antiparasitic,Disease,Antibacterial,Cancer,Wound Healing,Anti-oxidant,Protectant,Skin Permeation	Nerolidol	All	In Vitro,In Vivo	Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities
Protectant	Nerolidol	Liver	In Vitro	Hepatoprotection of sesquiterpenoids: A quantitative structure–activity relationship (QSAR) approach
Anti-oxidant,Cancer	Related pharmacology	Liver	In Vitro	THE POWER OF THE NRF2 PATHWAY
Safety	Nerolidol	N/A	N/A	BIOPESTICIDES REGISTRATION ACTION DOCUMENT: FARNESOL AND NEROLIDOL
Safety,Drug Interactions	Nerolidol	Liver	N/A	https://www.pharmacytimes.com/view/2007-11-8279
Insecticide	Nerolidol	Skin	In Silico	Design of a Repellent Against Aedes aegypti (Diptera: Culicidae) Using in silico Simulations With AaegOBP1 Protein
Cancer	Nerolidol	Lung	In Vitro	Cytotoxic mechanism of Piper gaudichaudianum Kunth essential oil and its major compound nerolidol
Pharmacology,Disease,Degenerative	Related pharmacology	N/A	In Vivo,In Vitro	The clinical potential of influencing Nrf2 signaling in degenerative and immunological disorders
Covid-19	Nerolidol	Lung	In Vivo,In Silico,In Vitro	Can Costus afer be used for co-treatment of COVID-19, its symptoms and comorbidities? A novel approach for combating the pandemic and implications for sub-Saharan Africa
Wound Healing	Nerolidol	Skin	In Vivo	Chitosan Hydrogel in combination with Nerolidol for healing wounds
Antibacterial	Nerolidol	N/A	In Vitro	Sensitization of Staphylococcus aureus and Escherichia coli to Antibiotics by the Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, and Apritone
Toxicity,Sensitivity	Nerolidol	N/A	In Vitro	A safety assessment of non-cyclic alcohols with unsaturated branched chain when used as fragrance ingredients: The RIFM expert panel
Disease,Covid-19,Antiviral,Inflammation	Nerolidol	Lung	In Vivo	COVID‑19 and therapy with essential oils having antiviral, anti‑inflammatory, and immunomodulatory properties
Antiparasitic	Nerolidol	N/A	In Vivo	Antiparasitic activity of nerolidol in a mouse model of schistosomiasis
Antibacterial	Nerolidol	Mouth	In Vitro	Antimicrobial potential of toothpaste formulated from extracts of Syzygium aromaticum, Dennettia tripetala and Jatropha curcas latex against some oral pathogenic microorganisms
Arthritis,Inflammation	Nerolidol	Joints	In Vivo	Anti-inflammatory effect of nano-encapsulated nerolidol on zymosan-induced arthritis in mice
Antifungal	Nerolidol	Skin	In Vitro	Antifungal Properties of Nerolidol-Containing Liposomes in Association with Fluconazole
Anti-oxidant	Nerolidol	Nervous System	In Silico	Anticonvulsant Essential Oils and Their Relationship with Oxidative Stress in Epilepsy
Men's Health	Nerolidol	Reproductive	In Vivo	Ameliorative effect of nerolidol on cyclophosphamide-induced gonadal toxicity in Swiss Albino mice: Biochemical-, histological- and immunohistochemical-based evidences
Anti-oxidant	Nerolidol	Heart,Kidney	In Vivo	The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
Antiparasitic	Nerolidol	Head	In Vivo	Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs
Inflammation	Nerolidol	N/A	In Vivo	A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action
Disease	Nerolidol	Nervous System	In Silico	Nerolidol and its Pharmacological Application in Treating Neurodegenerative Diseases: A Review
Inflammation	Nerolidol	Liver	In Vivo	Downregulation of hepatic fat accumulation, inflammation and fibrosis by nerolidol in purpose built western-diet-induced multiple-hit pathogenesis of NASH animal model
Cancer	Nerolidol	Colon	In Vivo	Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-l,6,10-dodecatriene (nerolidol)
Men's Health	Nerolidol	Reproductive	In Vitro,In Vivo	Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants
Antibacterial,Skin Permeation	Nerolidol	N/A	In Vitro	Effects of nerolidol and limonene on stratum corneum membranes: A probe EPR and fluorescence spectroscopy study
Antibacterial	Nerolidol	N/A	In Vitro	Selection of nerolidol among a series of terpenic and phenolic compounds for its potent activity against Lactobacillus fermentum ATCC 9338
Antibacterial	Nerolidol	Colon	In Vitro	Sensitivity of pathogenic and commensal bacteria from the human colon to essential oils
Enzymes	Nerolidol	Liver	In Vitro	Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
Women's Health	Nerolidol	N/A	In Vivo	Subfertile Female Androgen Receptor Knockout Mice Exhibit Defects in Neuroendocrine Signaling, Intraovarian Function, and Uterine Development But Not Uterine Function
Synergy,Metabolism	Nerolidol,β-caryophyllene	N/A	In Vivo	The impact of sesquiterpenes β-caryophyllene oxide and trans-nerolidol on xenobiotic-metabolizing enzymes in mice in vivo
Women's Health	Nerolidol	N/A	In Vivo	The beneficial effects of nerolidol and hesperidin on surgically induced endometriosis in a rat model