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Component Research

This is the summary of the activities of each component of essential oil from branch bark as published in medical and scientific journals.  This research is based on animal, laboratory, or computer analysis- and therefore is not evidence of its actual therapeutic effect in humans, only an indication of the possibility of such. The only human clinical trial was for human papilloma virus (HPV).

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Top 7 constituents in order (based on gc-ms reports)

 

    Constituent            Lo %        Hi %        Median %
trans-Nerolidol         54.0          64.8            59.4
Bicyclogermacrene    4.0           16.8            10.4
alpha-Muurolol          8.1           12.4             10.2
τ-Cadinol                     7.5           11.6              9.6
gamma-Cadinene      2.2           4.0               3.10
δ-Cadinene                 1.8            2.6               2.2
Spathulenol                0.4           3.2                1.8

1,10-di-epi-Cubenol

anti-cancer

https://www.ncbi.nlm.nih.gov/pubmed/26692745

Undeca-1,3,5-triene

cancer detection

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384920/

alpha-Cadinol

fungicide, anti-cancer, hepatitis prevention, anti-inflammatory

https://www.ncbi.nlm.nih.gov/pubmed/27534132

https://www.ncbi.nlm.nih.gov/pubmed/21872895

Germacrene D

anti-microbial, anti-inflammatory, antioxidant; tuberculosis treatment

https://www.ncbi.nlm.nih.gov/pubmed/30671730

https://www.ncbi.nlm.nih.gov/pubmed/30660710

https://www.ncbi.nlm.nih.gov/pubmed/22224302

Bulnesol

anti-cancer (lung), anti-inflammatory, cellular membrane stabilizer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320997/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323148/

 

Viridiflorol

anti-cancer (stomach), anti-inflammatory, antioxidant, tuberculosis treatment, Acetylcholinesterase inhibitor

https://www.ncbi.nlm.nih.gov/pubmed/26057223

https://www.ncbi.nlm.nih.gov/pubmed/27612433

Globulol

antimicrobial, antibacterial, antifungal, antioxidant, sedative, anaesthetic

www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400022&lng=en&tlng=en

https://www.ncbi.nlm.nih.gov/pubmed/18569693

Viridiflorene (Ledene)

tuberculosis treatment; tumor treatment

https://www.ncbi.nlm.nih.gov/pubmed/22224302

https://www.ncbi.nlm.nih.gov/pubmed/21227474

gamma-Elemene

insecticidal, antimicrobial, and antioxidant

https://www.ncbi.nlm.nih.gov/pubmed/28353108

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651734/

alpha-Muurolene

anti-inflammatory

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.200890022

beta-Elemene

anticancer

https://www.ncbi.nlm.nih.gov/pubmed/15868411

beta-Elemene

anticancer

https://www.ncbi.nlm.nih.gov/pubmed/15868411

trans-beta-Farnesene

aphid alarm pheremone, mosquito larvicide, antibacterial

http://europepmc.org/abstract/MED/22427877

https://www.ncbi.nlm.nih.gov/pubmed/26434140

Additional research on details of potential therapeutic activities of nerolidol

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