Components | Southeast Devilsclub

Component Research

This is the summary of the activities of each component of bark oil published in medical and scientific journals. This research is laboratory based, and therefore is not evidence of its actual therapeutic effect in humans, only an indication of the possibility of such. The only human clinical trial was for human papilloma virus (HPV).

trans-Nerolidol

antibacterial, antifungal, anti-inflammatory, anti-cancer, anti-tumor, anti-ulcer, antioxidant, anti-parasite (schistosomal, leishmanal, other), skin penetration enhancer, disease treatment (chagas, malaria, parkinson's), pain relief (anti-nociceptive), anti-biofilm (vs. surface-bacteria), AKI treatment (acute kidney injury), prevents ALI (acute lung injury) and damage from pneumonia, anti-seizure/epilepsy; cures HPV; insecticidal (mosquito), treats anxiety and depression; reduces damage from heart attacks ; neuroprotectant; liver protection

Details of potential therapeutic activities of nerolidol

alpha-Muurolol (=Torreyol)

antibacterial, antimicrobial; antioxidant; anti-cancer; anti-parasite, anti-tumor

Bicyclogermacrene

anti-fungal; anti-cancer (breast, cervical, colon, skin, brain); anti-parasite; anti-tumor;

Spathulenol

antioxidant, anti-inflammatory, antiproliferative, antimycobacterial, anticancer (gastric, leukemia, colon), leukemia, antiparasite (anti-malarial), antifungal; tuberculosis treatment; mosquito repellent; immunomodulatory; uterus relaxant

gamma-Cadinene

anti-ulcer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669120/

delta-Cadinene

women's health, anti-microbial, inhibit ovarian cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525816/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599884/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848531/

1,10-di-epi-Cubenol

anti-cancer

https://www.ncbi.nlm.nih.gov/pubmed/26692745

Undeca-1,3,5-triene

cancer detection

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384920/

alpha-Cadinol

fungicide, anti-cancer, hepatitis prevention, anti-inflammatory

https://www.ncbi.nlm.nih.gov/pubmed/27534132

https://www.ncbi.nlm.nih.gov/pubmed/21872895

Germacrene D

anti-microbial, anti-inflammatory, antioxidant; tuberculosis treatment

https://www.ncbi.nlm.nih.gov/pubmed/30671730

https://www.ncbi.nlm.nih.gov/pubmed/30660710

https://www.ncbi.nlm.nih.gov/pubmed/22224302

alpha-Pinene

anti-cancer, schizophrenia treatment, antibacterial, bronchitis treatment, anxiolytic, tumor treatment, antimicrobial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294613/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743669/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699265/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268287/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741888/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268778/

Germacrene B

cancer treatment (ovarian, lung, colon, stomach, and melanoma), tumor treatment, antimicrobial, insecticidal, antibacterial

https://www.ncbi.nlm.nih.gov/pubmed/15165160

https://www.ncbi.nlm.nih.gov/pubmed/23307235

https://www.ncbi.nlm.nih.gov/pubmed/30543916

https://pubchem.ncbi.nlm.nih.gov/pathway/PlantCyc:PLANT_PWY-5733

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143264/

https://www.ncbi.nlm.nih.gov/pubmed/31198053

beta-Sesquiphellandrene

antifungal, anti-cancer, antioxidant

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479355/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471621/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259104/

Bulnesol

anti-cancer (lung), anti-inflammatory, cellular membrane stabilizer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320997/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323148/

Viridiflorol

anti-cancer (stomach), anti-inflammatory, antioxidant, tuberculosis treatment, Acetylcholinesterase inhibitor

https://www.ncbi.nlm.nih.gov/pubmed/26057223

https://www.ncbi.nlm.nih.gov/pubmed/27612433

delta-Elemene

anti-tumor, anti-cancer (lung, pancreatic, colon)

https://www.ncbi.nlm.nih.gov/pubmed/21804218

https://www.ncbi.nlm.nih.gov/pubmed/31005810

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582541/

https://www.ncbi.nlm.nih.gov/pubmed/19881213

Guaiol

diuretic, laxative; antiparasitic; antibacterial; insecticide (termites); cancer treatment (lung); anti-inflammatory (treats/minimizes ankylosing spondylitis)

https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1401-9

https://link.springer.com/article/10.1007%2Fs10298-015-0966-7

https://link.springer.com/article/10.1007%2Fs10086-004-0683-6

https://www.ncbi.nlm.nih.gov/pubmed/27566579?dopt=Abstract

https://link.springer.com/article/10.1007%2Fs10787-017-0328-1

Globulol

antimicrobial, antibacterial, antifungal, antioxidant, sedative, anaesthetic

www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400022&lng=en&tlng=en

https://www.ncbi.nlm.nih.gov/pubmed/18569693

Viridiflorene (Ledene)

tuberculosis treatment; tumor treatment

https://www.ncbi.nlm.nih.gov/pubmed/22224302