Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.

Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category	Component	Body System	Type	Title
Inflammation,Disease	Nerolidol	Liver	In Vivo	Nerolidol protects the liver against cyclophosphamide-induced hepatic inflammation, apoptosis, and fibrosis via modulation of Nrf2, NF-κB p65, and caspase-3 signaling molecules in Swiss albino mice
Skin Permeation	Nerolidol	Skin	In Vitro	The effect of terpene concentrations on the skin penetration of diclofenac sodium
Anti-oxidant,Disease	Nerolidol	Heart	In Vivo	Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats
Anti-oxidant,Cancer	Nerolidol	N/A	In Vivo	Anticancer and antioxidant profiling effects of Nerolidol against DMBA induced oral experimental carcinogenesis
Cancer	Nerolidol	Bone	In Vitro	Nerolidol induced apoptosis via PI3K/JNK regulation through cell cycle arrest in MG-63 osteosarcoma cells
Anti-oxidant,Arthritis,Inflammation	Nerolidol	Skeletal	In Vivo	Nerolidol: a potential approach in rheumatoid arthritis through reduction of TNF-α, IL-1β, IL-6, NF-kB, COX-2 and antioxidant effect in CFA-induced arthritic model
Antibacterial	Nerolidol	N/A	In Vitro	Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol
Antibacterial	Nerolidol	N/A	In Vitro	Effect of the essential oils from Piper sp. and blue led lights in the enhancement of the antibiotic activity of drugs against mdr bacterial strains
Antibacterial	Nerolidol	N/A	In Vitro	Evaluation of the antioxidant, antibacterial, and antibiofilm activity of the sesquiterpene nerolidol
Anti-oxidant,Protectant	Nerolidol	N/A	In Vivo	Dietary supplementation with nerolidol improves the antioxidant capacity and muscle fatty acid profile of Brycon amazonicus exposed to acute heat stress
Inflammation,Anti-oxidant	Nerolidol	Colon	In Vivo	Nerolidol, a sesquiterpene, attenuates oxidative stress and inflammation in acetic acid-induced colitis in rats
Protectant,Anxiolytic	Nerolidol	Nervous System	In Vivo	Assessment of anxiolytic effect of nerolidol in mice
Protectant	Alpha-Pinene	Nervous System	In Vivo	Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
Protectant,Anti-oxidant,Disease	Related pharmacology	Nervous System	In Vivo	Transcriptional Regulation by Nrf2
Pharmacology	Related pharmacology	Nervous System	In Vitro	Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration