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Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.


​Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category
Component
Body System
Type
Title
Disease
Related pharmacology
Kidney
In Vivo
L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
Anti-oxidant,Disease
Related pharmacology
Thyroid
In Vivo
The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism
Protectant
Related pharmacology
Heart
In Vivo
Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1
Aging
Related pharmacology
N/A
In Vivo
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
Anti-oxidant,Protectant
Related pharmacology
N/A
In Vitro
Glucose availability is a decisive factor for Nrf2-mediated gene expression
Cancer
Related pharmacology
N/A
In Vitro
The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer
Disease
Related pharmacology
Heart
In Vitro,In Vivo
Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies
Cancer
Nerolidol
Liver
In Vitro
Nerolidol effects on mitochondrial and cellular energetics
Pharmacology
Oplopanax Horridus
All
In Vivo
TRADITIONAL USE OF DEVIL'S-CLUB (OPLOPANAX HORRIDUS; ARALIACEAE) BY NATIVE PEOPLES IN WESTERN NORTH AMERICA
Pharmacology,Cancer
Oplopanax Horridus
N/A
In Vitro
Oplopanax horridus: Phytochemistry and Pharmacological Diversity and Structure-Activity Relationship on Anticancer Effects
Cancer
Oplopanax Horridus
Lung,Breast
In Vitro
Improving anticancer activities of Oplopanax horridus root bark extract by removing water-soluble components
Antiparasitic
Nerolidol
N/A
In Vitro
Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum
Antiparasitic
Nerolidol
N/A
In Vitro
Terpenes Arrest Parasite Development and Inhibit Biosynthesis of Isoprenoids in Plasmodium falciparum
Insecticide
Nerolidol
N/A
In Vivo
Mosquito Repellent Potential of Carpesium abrotanoides Essential Oil and Its Main Components Against a Dengue Vector
Anti-oxidant,Protectant
Nerolidol
Heart,Kidney
In Vivo
The Ameliorate Effects of Nerolidol on Thioacetamide-induced Oxidative Damage in Heart and Kidney Tissue
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