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Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.


​Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category
Component
Body System
Type
Title
Anti-oxidant,Protectant
Related pharmacology
Brain
In Vitro
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
Degenerative,Protectant,Disease
Related pharmacology
Nervous System
In Vitro,In Vivo
Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
Anti-oxidant,Protectant,Disease
Related pharmacology
Kidney
In Vitro
Keap1/Nrf2/ARE signaling unfolds therapeutic targets for redox imbalanced-mediated diseases and diabetic nephropathy
Anti-oxidant,Disease
Related pharmacology
Immune System
In Vitro
How the redox state regulates immunity
Anti-oxidant
Related pharmacology
Nervous System
In Vitro,In Vivo
Nrf2-Keap1 signaling in oxidative and reductive stress
Inflammation
Related pharmacology
Nervous System
In Vitro,In Vivo
Nrf2 signaling pathway: Pivotal roles in inflammation
Protectant
Related pharmacology
Nervous System
In Vitro
The emerging role of Nrf2 in mitochondrial function
Protectant,Degenerative
Related pharmacology
Nervous System
In Silico,In Vitro
Structural basis of Keap1 interactions with Nrf2
Inflammation,Toxicity
Nerolidol
Nervous System
In Vivo
Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity - Probable role of NLRP3 inflammasome and caspase-1
Aging,Degenerative
Related pharmacology
Brain
In Vivo
Selective noradrenaline depletion impairs working memory and hippocampal neurogenesis
Antibacterial
Torreyol
N/A
In Vitro
ANTIBACTERIAL AND ANTIFUNGAL TERPENES FROM Pilgerodendron uviferum (D. DON) FLORIN
Inflammation,Anti-oxidant
Related pharmacology
Nervous System
In Silico,In Vitro
Neurobiological Basis of Increased Risk for Suicidal Behaviour
Covid-19,Metabolism
Related pharmacology
All
In Vivo
Metabolic rewiring and serotonin depletion in patients with postacute sequelae of COVID-19
Disease,Aging,Anti-oxidant,Protectant,Degenerative
Related pharmacology
Nervous System,Cellular
In Silico
Redox regulation by NRF2 in aging and disease
Anti-oxidant
Related pharmacology
Kidney
In Vivo
L-ergothioneine and its combination with metformin attenuates renal dysfunction in type-2 diabetic rat model by activating Nrf2 antioxidant pathway
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