Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.

Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category	Component	Body System	Type	Title
Protectant	Related pharmacology	Cellular	In Silico,In Vitro	Beyond repression of Nrf2: An update on Keap1
Pharmacology	Related pharmacology	Immune System	In Vitro	ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen
Cancer	Oplopanax Horridus	Colon,Breast	In Vitro	Hydrophobic constituents and their potential anticancer activities from Devil’s Club Oplopanax horridus
Protectant	Nerolidol	Heart	In Vivo	Small Molecule Compound Nerolidol attenuates Hypertension induced hypertrophy in spontaneously hypertensive rats through modulation of Mel-18-IGF-IIR signaling
Protectant	Nerolidol	Lung	In Vivo	Protective effect of nerolidol on lipopolysaccharide-induced acute lung injury through the inhibition of NF-κB activation by the reduction of p38 MAPK and JNK phosphorylation
Protectant	Nerolidol	Liver,Bone	In Vivo	Effect of nerolidol on cyclophosphamide-induced bone marrow and hematologic toxicity in Swiss albino mice
Anti-oxidant,Antibacterial	Nerolidol	Brain	In Vivo	Benefits of nanotechnology: Dietary supplementation with nerolidol-loaded nanospheres increases survival rates, reduces bacterial loads and prevents oxidative damage in brains of Nile tilapia experimentally infected by Streptococcus agalactiae
Antiparasitic	Nerolidol	N/A	In Vitro	In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway
Women's Health	Nerolidol	Reproductive	In Silico	An Assay on the Possible Effect of Essential Oil Constituents on Receptors Involved in Women’s Hormonal Health and Reproductive System Diseases
Skin Permeation	Nerolidol	Skin	In Vitro	Toxicity of terpenes on fibroblast cells compared to their hemolytic potential and increase in erythrocyte membrane fluidity
Insecticide	Nerolidol	N/A	In Vivo	Toxicity of Juniperus oxycedrus oil constituents and related compounds and the efficacy of oil spray formulations to Dermatophagoides farinae (Acari: Pyroglyphidae)
Antifungal	Nerolidol	N/A	In Vitro	The Sensitivity Modifying Activity of Nerolidol and α-Bisabolol Against Trichophyton spp
Protectant,Anti-oxidant	Nerolidol	All	In Vitro,In Vivo	Terpenoids as Potential Geroprotectors
Covid-19	Related pharmacology	Lung	In Vitro	SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Covid-19	Nerolidol	Lung	In Silico,In Vitro	Role of botanical essential oils as a therapy for controlling coronavirus (SARS-CoV-2) disease (Covid-19)