Research Articles

Due to differences in animal/human physiology the findings of in vivo studies cannot be translated to effects on human health. In vitro studies on cell cultures also do not guarantee results in humans.

Findings may be an indicator of potential results in humans. Clinical trials are needed to verify extrapolations from laboratory tests.

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Category	Component	Body System	Type	Title
Anti-nociceptive,Pain Management,Inflammation	Nerolidol	All	In Vivo	Nerolidol exhibits antinociceptive and anti‐inflammatory activity: involvement of the GABAergic system and proinflammatory cytokines
Pharmacology	Nerolidol	Liver	In Vivo	Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
Anti-oxidant,Inflammation	Nerolidol	Nervous System	In Vivo	Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: Plausible role of Nrf2 and NF- κB
Toxicity	Nerolidol	N/A	N/A	Addendum to Fragrance material review on Nerolidol (isomer unspecified)
Anti-diabetic	Nerolidol	Liver	In Vitro	Invitroantidiabetic Activity of Nerolidol: An Active Compound Isolated From Alpinia Calcarata
Antiparasitic	Nerolidol	N/A	In Vivo	Inhibitory effect of terpene nerolidol on the growth of Babesia parasites
Toxicity	Nerolidol	All	In Vivo	In vivo genotoxicity assessment of nerolidol
Antiviral,Covid-19	Nerolidol	Lung	In Silico	Essential Oils as Antiviral Agents, Potential of Essential Oils to Treat SARS-CoV-2 Infection: An In-Silico Investigation
Antiparasitic,Disease,Antibacterial,Cancer,Wound Healing,Anti-oxidant,Protectant,Skin Permeation	Nerolidol	All	In Vitro,In Vivo	Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities
Protectant	Nerolidol	Liver	In Vitro	Hepatoprotection of sesquiterpenoids: A quantitative structure–activity relationship (QSAR) approach
Anti-oxidant,Cancer	Related pharmacology	Liver	In Vitro	THE POWER OF THE NRF2 PATHWAY
Safety	Nerolidol	N/A	N/A	BIOPESTICIDES REGISTRATION ACTION DOCUMENT: FARNESOL AND NEROLIDOL
Safety,Drug Interactions	Nerolidol	Liver	N/A	https://www.pharmacytimes.com/view/2007-11-8279
Insecticide	Nerolidol	Skin	In Silico	Design of a Repellent Against Aedes aegypti (Diptera: Culicidae) Using in silico Simulations With AaegOBP1 Protein
Cancer	Nerolidol	Lung	In Vitro	Cytotoxic mechanism of Piper gaudichaudianum Kunth essential oil and its major compound nerolidol